| KY: Lexington (Satellite TV) | | 14 | - | CW | Some Programs On CW: America's Next Top Model, Jericho, Supernatural, The Game, Gossip Girl, The Drew Carey Show, Smallville, 90210, Stylista, Privileged, Everybody Hates Chris, One Tree Hill, and Reaper. | Local | - |
| 18 | 18 | WLEX | Some Programs On NBC: Friday Night Lights, America's Got Talent, The Apprentice, Late Night with Conan O'Brien, Law & Order, Early Today, Main article: qubo, Preakness Stakes, Wimbledon Tennis, Kings, Jacob Two Two, The Biggest Loser, and The NHL. | Local | Local |
| 27 | 27 | WKYT | Some Programs On CBS: As the World Turns, The New Adventures of Old Christine, Million Dollar Password, CSI: NY, Guiding Light, Trollz, Sushi Pack, The Saturday Early Show, Cold Case, The Masters, US Open Tennis, NCIS, and CBS Evening News. | Local | Local |
| 36 | 36 | WTVQ | Some Programs On ABC: According to Jim, Extreme Makeover: Home Edition, Life on Mars, Nightline, Academy Awards, I Survived A Japanese Game Show, America's Funniest Home Videos, Ugly Betty, Scrubs, British Open, Boston Legal, The Bachelor, and NBA on ABC. | Local | Local |
| 46 | 46 | WKLE | Some Programs On PBS: Fetch! With Ruff Ruffman, Frontline, Design Squad, Thomas and Friends, Danger Rangers, Nightly Business Report, American Masters, Zoboomafoo, DragonflyTV, The Fitness Show, Wide Angle, The Victory Garden, and Charlie Rose. | Local | Local |
| 56 | 56 | WDKY | Some Programs On FOX: Hell's Kitchen, Major League Baseball on FOX, COPS, Family Guy, Terminator: The Sarah Connor Chronicles, NFL on FOX/FOX NFL Sunday, American Dad!, America's Most Wanted: America Fights Back, 24, Prison Break, Teen Choice Awards, Hole in the Wall, and So You Think You Can Dance. | Local | Local |
| - | 65 | WLJC | WLJC (IND) | - | Local |
| KY: Louisville (Satellite TV) | | 3 | 3 | WAVE | Some Programs On NBC: Friday Night Lights, America's Got Talent, The Apprentice, Late Night with Conan O'Brien, Law & Order, Early Today, Main article: qubo, Preakness Stakes, Wimbledon Tennis, Kings, Jacob Two Two, The Biggest Loser, and The NHL. | Local | Local |
| 11 | 11 | WHAS | Some Programs On ABC: According to Jim, Extreme Makeover: Home Edition, Life on Mars, Nightline, Academy Awards, I Survived A Japanese Game Show, America's Funniest Home Videos, Ugly Betty, Scrubs, British Open, Boston Legal, The Bachelor, and NBA on ABC. | Local | Local |
| 15 | 15 | WKPC | Some Programs On PBS: Fetch! With Ruff Ruffman, Frontline, Design Squad, Thomas and Friends, Danger Rangers, Nightly Business Report, American Masters, Zoboomafoo, DragonflyTV, The Fitness Show, Wide Angle, The Victory Garden, and Charlie Rose. | Local | Local |
| 21 | - | ION | ION (ION) | Local | - |
| - | 21 | WBNA | WBNA (Rel) | - | Local |
| 32 | 32 | WLKY | Some Programs On CBS: As the World Turns, The New Adventures of Old Christine, Million Dollar Password, CSI: NY, Guiding Light, Trollz, Sushi Pack, The Saturday Early Show, Cold Case, The Masters, US Open Tennis, NCIS, and CBS Evening News. | Local | Local |
| 34 | 34 | WBKI | Some Programs On CW: America's Next Top Model, Jericho, Supernatural, The Game, Gossip Girl, The Drew Carey Show, Smallville, 90210, Stylista, Privileged, Everybody Hates Chris, One Tree Hill, and Reaper. | Local | Local |
| 41 | 41 | WDRB | Some Programs On FOX: Hell's Kitchen, Major League Baseball on FOX, COPS, Family Guy, Terminator: The Sarah Connor Chronicles, NFL on FOX/FOX NFL Sunday, American Dad!, America's Most Wanted: America Fights Back, 24, Prison Break, Teen Choice Awards, Hole in the Wall, and So You Think You Can Dance. | Local | Local |
| 58 | 58 | WMYO | WMYO (MNT) | Local | Local |
| 68 | 68 | WKMJ | Some Programs On PBS: Fetch! With Ruff Ruffman, Frontline, Design Squad, Thomas and Friends, Danger Rangers, Nightly Business Report, American Masters, Zoboomafoo, DragonflyTV, The Fitness Show, Wide Angle, The Victory Garden, and Charlie Rose. | Local | Local |
| KY: Paducah-MO: Cape Girardeau (Satellite TV) | | 8 | 8 | WSIU | Some Programs On PBS: Fetch! With Ruff Ruffman, Frontline, Design Squad, Thomas and Friends, Danger Rangers, Nightly Business Report, American Masters, Zoboomafoo, DragonflyTV, The Fitness Show, Wide Angle, The Victory Garden, and Charlie Rose. | Local | Local |
| 23 | 23 | KBSI | Some Programs On FOX: Hell's Kitchen, Major League Baseball on FOX, COPS, Family Guy, Terminator: The Sarah Connor Chronicles, NFL on FOX/FOX NFL Sunday, American Dad!, America's Most Wanted: America Fights Back, 24, Prison Break, Teen Choice Awards, Hole in the Wall, and So You Think You Can Dance. | Local | Local |
| - | 27 | WTCT | WTCT (TCT) | - | Local |
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