| MO: Columbia-Jefferson City (Satellite TV) | | 6 | 6 | KMOS | Some Programs On PBS: History Detectives, Animusic, DragonflyTV, Mustard Pancakes, The Electric Company, Tavis Smiley, Between the Lions, American Experience, Tony Brown's Journal, Zula Patrol, Mystery!, Religion & Ethics Newsweekly, and Thomas and Friends. | Local | Local |
| 8 | 8 | KOMU | Some Programs On NBC: Law & Order: Special Victims Unit, Crusoe, Main article: NBC Sports, America's Got Talent, Last Comic Standing, Jane and the Dragon, America's Toughest Jobs, WWE Saturday Night's Main Event, PGA Tour Golf, Wimbledon Tennis, 3-2-1 Penguins! / Larry-Boy Stories, The Apprentice, and ER. | Local | Local |
| - | 11 | KZOU | KZOU (MyTV) | - | Local |
| 13 | 13 | KRCG | Some Programs On CBS: Formula One, Two and a Half Men, Survivor, Vitalis Sun Bowl, The Young and the Restless, The Late Show with David Letterman, Criminal Minds, Crimetime Saturday, Guiding Light, The Price Is Right, Care Bears: Adventures In Care-A-Lot, CBS Morning News, and Eleventh Hour. | Local | Local |
| 14 | - | CW | Some Programs On CW: 90210, America's Next Top Model, Reaper, Everybody Hates Chris, Supernatural, Stylista, Gossip Girl, Smallville, The Game, The Drew Carey Show, One Tree Hill, Jericho, and Privileged. | Local | - |
| 17 | 17 | KMIZ | Some Programs On ABC: Major League Soccer, Belmont Stakes, Breeders' Cup, Desperate Housewives, The View, WNBA, According to Jim, Saturday Night College Football, NBA on ABC, Wipeout, Academy Awards, Good Morning America, and Rose Bowl. | Local | Local |
| 25 | 25 | KNLJ | KNLJ (IND) | Local | Local |
| 38 | 38 | KQFX | Some Programs On FOX: Dollhouse, American Idol, Teen Choice Awards, Kitchen Nightmares, Terminator: The Sarah Connor Chronicles, The Simpsons, The Moment of Truth, Talkshow with Spike Feresten, Fringe, Lie to Me, NASCAR on FOX, Prison Break, and Major League Baseball on FOX. | Local | Local |
| MO: Springfield (Satellite TV) | | 3 | 3 | KYTV | Some Programs On NBC: Law & Order: Special Victims Unit, Crusoe, Main article: NBC Sports, America's Got Talent, Last Comic Standing, Jane and the Dragon, America's Toughest Jobs, WWE Saturday Night's Main Event, PGA Tour Golf, Wimbledon Tennis, 3-2-1 Penguins! / Larry-Boy Stories, The Apprentice, and ER. | Local | Local |
| 10 | 10 | KOLR | Some Programs On CBS: Formula One, Two and a Half Men, Survivor, Vitalis Sun Bowl, The Young and the Restless, The Late Show with David Letterman, Criminal Minds, Crimetime Saturday, Guiding Light, The Price Is Right, Care Bears: Adventures In Care-A-Lot, CBS Morning News, and Eleventh Hour. | Local | Local |
| 15 | - | KCZ | Some Programs On CW: 90210, America's Next Top Model, Reaper, Everybody Hates Chris, Supernatural, Stylista, Gossip Girl, Smallville, The Game, The Drew Carey Show, One Tree Hill, Jericho, and Privileged. | Local | - |
| - | 15 | KDL | Some Programs On CW: 90210, America's Next Top Model, Reaper, Everybody Hates Chris, Supernatural, Stylista, Gossip Girl, Smallville, The Game, The Drew Carey Show, One Tree Hill, Jericho, and Privileged. | - | Local |
| 21 | 21 | KOZK | Some Programs On PBS: History Detectives, Animusic, DragonflyTV, Mustard Pancakes, The Electric Company, Tavis Smiley, Between the Lions, American Experience, Tony Brown's Journal, Zula Patrol, Mystery!, Religion & Ethics Newsweekly, and Thomas and Friends. | Local | Local |
| 27 | 27 | KSFX | Some Programs On FOX: Dollhouse, American Idol, Teen Choice Awards, Kitchen Nightmares, Terminator: The Sarah Connor Chronicles, The Simpsons, The Moment of Truth, Talkshow with Spike Feresten, Fringe, Lie to Me, NASCAR on FOX, Prison Break, and Major League Baseball on FOX. | Local | Local |
| 31 | 31 | KWBM | KWBM (MNT) | Local | Local |
| 33 | 33 | KSPR | Some Programs On ABC: Major League Soccer, Belmont Stakes, Breeders' Cup, Desperate Housewives, The View, WNBA, According to Jim, Saturday Night College Football, NBA on ABC, Wipeout, Academy Awards, Good Morning America, and Rose Bowl. | Local | Local |
| MO: St. Louis (Satellite TV) | | 2 | 2 | KTVI | Some Programs On FOX: Dollhouse, American Idol, Teen Choice Awards, Kitchen Nightmares, Terminator: The Sarah Connor Chronicles, The Simpsons, The Moment of Truth, Talkshow with Spike Feresten, Fringe, Lie to Me, NASCAR on FOX, Prison Break, and Major League Baseball on FOX. | Local/HD | Local/HD |
| 4 | 4 | KMOV | Some Programs On CBS: Formula One, Two and a Half Men, Survivor, Vitalis Sun Bowl, The Young and the Restless, The Late Show with David Letterman, Criminal Minds, Crimetime Saturday, Guiding Light, The Price Is Right, Care Bears: Adventures In Care-A-Lot, CBS Morning News, and Eleventh Hour. | Local/HD | Local/HD |
| 5 | 5 | KSDK | Some Programs On NBC: Law & Order: Special Victims Unit, Crusoe, Main article: NBC Sports, America's Got Talent, Last Comic Standing, Jane and the Dragon, America's Toughest Jobs, WWE Saturday Night's Main Event, PGA Tour Golf, Wimbledon Tennis, 3-2-1 Penguins! / Larry-Boy Stories, The Apprentice, and ER. | Local/HD | Local/HD |
| 9 | 9 | KETC | Some Programs On PBS: History Detectives, Animusic, DragonflyTV, Mustard Pancakes, The Electric Company, Tavis Smiley, Between the Lions, American Experience, Tony Brown's Journal, Zula Patrol, Mystery!, Religion & Ethics Newsweekly, and Thomas and Friends. | Local | Local |
| 11 | 11 | KPLR | Some Programs On CW: 90210, America's Next Top Model, Reaper, Everybody Hates Chris, Supernatural, Stylista, Gossip Girl, Smallville, The Game, The Drew Carey Show, One Tree Hill, Jericho, and Privileged. | Local | Local |
| 13 | 13 | WPXS | WPXS (IND) | Local | Local |
| 24 | 24 | KNLC | KNLC (IND) | Local | Local |
| 30 | 30 | KDNL | Some Programs On ABC: Major League Soccer, Belmont Stakes, Breeders' Cup, Desperate Housewives, The View, WNBA, According to Jim, Saturday Night College Football, NBA on ABC, Wipeout, Academy Awards, Good Morning America, and Rose Bowl. | Local/HD | Local/HD |
| 46 | 46 | WRBU | WRBU (MNT) | Local | Local |
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